Wednesday, January 16, 2008

Absorbable collagen (dental): Drug information

Copyright 1978-2006 Lexi-Comp, Inc. All rights reserved.

U.S. BRAND NAMES — CollaCote®; CollaPlug®; CollaTape®
PHARMACOLOGIC CATEGORY Hemostatic Agent
DOSING: ADULTS — Control of bleeding: Topical: A sufficiently large dressing should be selected so as to completely cover the oral wound
DOSING: PEDIATRIC — Refer to adult dosing.
DOSING: ELDERLY — Refer to adult dosing.
DOSAGE FORMS — Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Wound dressing:
3/8" x 3/4"
3/4" x 1 1/2"
1" x 3"
DOSAGE FORMS: CONCISE Wound dressing: Generics: 3/8" x 3/4" 3/4" x 1 1/2" 1" x 3" Brands: CollaCote®, CollaPlug®, CollaTape®: 3/8" x 3/4" 3/4" x 1 1/2" 1" x 3"
GENERIC EQUIVALENT AVAILABLE — Yes
USE — Hemostatic
ADVERSE REACTIONS SIGNIFICANT — No data reported.
CONTRAINDICATIONS — No data reported
WARNINGS / PRECAUTIONS — Should not be used on infected or contaminated wounds
DRUG INTERACTIONS — No data reported
LACTATION — Compatible
MECHANISM OF ACTION — The highly porous sponge structure absorbs blood and wound exudate. The collagen component causes aggregation of platelets which bind to collagen fibrils. The aggregated platelets degranulate, releasing coagulation factors that promote the formation of fibrin.
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